Endocrine Abstracts

Background and aims: Neuropeptide Y (NPY) cause decrease glomerular filtration rate, aldosterone concentration, and plasma renin activity by stimulating NPY receptors in the kidney. Previous studies have suggested that NPY polymorphism is related to development of advanced diabetic nephropathy (DN). The aim of this study was to evaluate the relationship between the serum neuropeptide Y levels and different stages of DN in patients with type 2 diabetes mellitus (T2DM).<p cl...

Introduction: Polycystic ovary syndrome (PCOS) is widely diagnosed among young women in reproductive age. Vitamin D deficiency has been known as a common problem in all ages and also in a recent study which performed in a small study groups, reported that it may accompany with hyperandrogenism. The aim of our study is to evaluate serum 25(OH)D3 levels in PCOS patients compared with healthy control and relation to androgen levels.Methods: Forty...

Background and aims: Hypovitaminosis D may be associated with metabolic parameters in addition to its well-known calcemic actions. There is increasing evidence that vitamin D metabolism affects the risk of insulin resistance although the underlying molecular mechanism of this association is not clear but on the basis of evidence it is not clear whether or not vitamin D supplementation therapy in vitamin D-deficient prediabetics affects the prevention of type 2 diabetes. Our st...

Objective: Recent recommendations suggest that HbA1c as a stable and standardised index of chronic glucose exposure over time and could be used as a better biochemical marker for the diagnosis of diabetes and prediabetes. Our aim in this cross-sectional study is to assess the validity of HbA1c as a screening tool for the detection of prediabetes in our patient population.Methods: The study was done in 265 patients selected among the participants attended...